Overview (Bear Tracks)

Congenital grouped pigmentation of the RPE (CGP-RPE) and its non-pigmented variation, grouped congenital albinotic retinal pigment epithelial spots (GCARPES) are congenital small, flat RPE lesions that may affect any part of the retina, but typically spares the macula.

CGP-RPE are characterised by groups of small, well defined pigmented lesions that mimic animal footprints or paws. This condition is also termed as ‘bear tracks’. They can be found in a single sector or quadrant of the fundus and its size typically increases towards the periphery.

OCT imaging through the CGP-RPE can be variable. Some may show no detectable change but some may display RPE thickening, posterior shadowing with conformational elevation of the ellipsoid zone.

FAF typically shows a uniform hypo-autofluorescent signal. However, hyper autofluorescence has also been described which suggests RPE dysfunction or developing atrophy.

Overview (Polar Bear Tracks)

Related to CGP-RPE are grouped congenital albinotic retinal pigment epithelial spots (GCARPES).

Funduscopic features of GCARPES include groups of small, flat hypopigmented lesions which can be distributed in a single sector or quadrant of the fundus. Its distribution is similar to CGP-RPE and is commonly referred to as polar bear tracks.

OCT imaging can show focal RPE thickening and disruption of the ellipsoid zone

FAF imaging can display both hyper and hypo autofluorescence.

Case Examples

Differential Diagnosis (Bear Tracks)

Differential Diagnosis (Polar Bear Tracks)

References

Ly, A. Nivison-Smith, L. Hennessy, M. Kalloniatis, M. (2015) Pigmented Lesions of the Retinal Pigment Epithelium, Optometry and Vision Science: Volume 92 - Issue 8.

Raval et al., 2019. Multimodal imaging of congenital hypertrophy of the retinal pigment epithelium (CHRPE) lesions at different presentations

Wang et al., 2020. Multimodal imaging characteristics of congenital grouped hyper- and hypo-pigmented fundus lesion. Clin Exp Optom, 103: 641-647.