Overview
Sclerochoroidal calcification occurs due to calcium deposition at the level of the sclera and choroid. It is typically idiopathic but it may be associated with abnormal calcium-phosphorus metabolism or renal tubular hypokalemic metabolic alkalosis syndrome. It is most often seen in older Caucasian males.
Funduscopic features include multiple discrete yellow placoid lesions typically found in the superotemporal post-equatorial retina.
OCT showed scleral elevations with compression of the overlying choroid and RPE abnormalities. The shape of the sclerochoroial calcification on OCT has been described in ‘mountain-like’ patterns including flat, rolling, rocky-rolling and table mountain.
FAF can show iso- or hyper- autofluorescence
B-scan ultrasound shows a hyper echoic area with posterior shadowing.
Case Examples
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Case 1
An asymptomatic 85 year old Caucasian male with best corrected visual acuity of 6/6 (20/20) in each eye.
Optomap (1) red separation (2) and green separation (3) images - Right eye
More infoFundus autofluorescence image (right eye)
More infoSpectralis OCT line scans through the right superior temporal lesion
More infoOptomap (1) red separation (2) and green separation (3) images - Left eye
More infoFundus autofluorescence image (left eye)
More infoSpectralis OCT line scan through the left superior temporal lesion
More infoSpectralis OCT volume scan through the left superior temporal lesion
More info
Differential diagnosis
Hasanreisoglu, M., Saktanasate, J., Shields, P. W., & Shields, C. L. (2015). Classification of sclerochoroidal calcification based on enhanced depth imaging optical coherence tomography “mountain-like” features. Retina, 35(7), 1407-1414.
Honavar, S. G., Shields, C. L., Demirci, H., & Shields, J. A. (2001). Sclerochoroidal calcification: clinical manifestations and systemic associations. Archives of Ophthalmology, 119(6), 833-840.
Shields, C. L., Hasanreisoglu, M., Saktanasate, J., Shields, P. W., Seibel, I., & Shields, J. A. (2015). Sclerochoroidal calcification: clinical features, outcomes, and relationship with hypercalcemia and parathyroid adenoma in 179 eyes. Retina, 35(3), 547-554.