Overview
Early AMD is characterised by medium sized drusen (63 to 125µm) with no pigmentary abnormalities. There should be no characteristics of intermediate or late AMD.
On OCT, drusen appear as dome-shaped or nodular elevations of the RPE with medium internal reflectivity.
Fundus autofluorescence imaging show a variable autofluorescence pattern. They may show a hyper- or hypo-autofluorescent pattern but may also be iso-autofluorescent.
Case Examples
Differential diagnosis
References
Ferris, CP. Wilkinson, AB, Chakravarthy, U. Chew, E. Csaky, K. Sadda, SR. (2013) Clinical Classification of Age-related Macular Degeneration, Ophthalmology, Volume 120, Issue 4, Pages 844-851.